Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 4 4 2007 12 15 189 192 A. Khorsand Associate Professor, Department of Periodontics, School of Dentistry, Tehran University of Medical S G. Saaveh Assistant Professor, Department of Periodontics, School of Dentistry, Ahvaz University of Medical Sc 2015 10 03 Amyloidosis includes a wide range of disorders characterized by deposition of amyloid in different organs and tissues. Localized gingival enlargement due to accumulation of amyloid without involvement of other organs is a very rare condition. This article describes a 31-year-old male patient with amyloidosis involving only the periodontium of the anterior mandibular teeth with localized severe horizontal alveolar bone loss. To our knowledge this is the first case report that documents this condition. https://fid.tums.ac.ir/index.php/fid/article/view/137 https://fid.tums.ac.ir/index.php/fid/article/download/137/137