Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 5 1 2008 03 15 7 11 S. Shahabi Associate Professor, Department of Dental Materials, School of Dentistry, Tehran University of Medic F. Pesaran Dentist, Private Practice MJ. Kharazifard Statistical Consultant, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 2015 10 03 Objective: The main purpose of this study was to develop a simple reproducible system to compare abrasive effects of three different toothpastes. Materials and Methods: A specific mold was used to fabricate 37 samples made of po-lymethylmethacrylate. The samples were stroke by toothbrushes connected to a V8 Cross Brushing Machine in a solution of fluoridated toothpastes and distilled water. The samples were evaluated initially and also after 48 hours. The data were analyzed by one-way ANOVA test. Results: No significant differences was found among the three types of toothpastes after 25000 strokes (P=0.427). Conclusion: All the three toothpastes presented same abrasive properties. https://fid.tums.ac.ir/index.php/fid/article/view/139 https://fid.tums.ac.ir/index.php/fid/article/download/139/139