Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 5 4 2008 12 15 156 160 Z. Jaberi Ansari Associate Professor, Department of Operative Dentistry, School of Dentistry, Shahid Beheshti Univers SM. Hashemi Associate Professor, Department of Orthodontics, School of Dentistry, Shiraz University of Medical S 2015 10 03 Objective: The aim of this study was to evaluate the efficacy of enamel bonding agents on pit and fissure sealant retention in a well-isolated situation. Materials and Methods: Thirty-two patients (6-9 years old, all males) with four fully erupted permanent first molars were selected. Their occlusal, buccal, and lingual fissures were sealed according to a split-mouth design using concise light curing white sealant (3M) for the control group and Heliobond (Vivadent) plus sealant for the study group. The retention of sealants was carefully inspected after one year and the data were analyzed by chi-square test. Results: The percentages of complete retention in the study and control groups were 73.2, and 71.4, respectively. Chi-square test revealed no significant difference between these groups (P>0.05) Conclusion: In a dry and isolated situation, application of enamel bonding agent has no significant effect on fissure sealant retention. https://fid.tums.ac.ir/index.php/fid/article/view/165 https://fid.tums.ac.ir/index.php/fid/article/download/165/165