Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 14 6 2017 12 16 361 365 EN Gholamreza Shirani Assistant Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Mahnaz Arshad Assistant Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Prosthodontics, School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran, Iran Xaniar Mahmoudi Dental Student, School of Dentistry, International Campus, Tehran University of Medical Sciences, Tehran, Iran Sergic Azarians Neurologist, Private Practice, Tehran, Iran 2017 05 23 2017 11 03 It is estimated that one-third of the people with refractory epilepsy suffer from obstructive sleep apnea (OSA). In a patient presenting with OSA symptoms and epilepsy, removing a portion of the soft palate (uvulopalatoplasty) can be considered the treatment of choice for eliminating the OSA and decreasing the seizures.Here, we report the results of our surgical approach by which the patient’s problems completely resolved, and we observed no symptoms of OSA or epilepsy after the surgery. After 10 years of follow-up, the patient is seizure-free and does not need any antiepileptic drugs. https://fid.tums.ac.ir/index.php/fid/article/view/1917 https://fid.tums.ac.ir/index.php/fid/article/download/1917/983