Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 16 3 2019 05 29 230 237 EN Shaik Izaz Department of Conservative Dentistry and Endodontics, Sibar Institute of Dental Sciences, Guntur, India Nagesh Bolla Department of Conservative Dentistry and Endodontics, Sibar Institute of Dental Sciences, Guntur, India Bhargavi Dasari Oral and Maxillofacial Radiology, Rutgers School of Dental Medicine, Newark, New Jersey Arka Prova Bhattacharjee Department of Conservative Dentistry and Endodontics, Sibar Institute of Dental Sciences, Guntur, India 2017 07 18 2019 01 08 The success of nonsurgical endodontic management depends on the complete elimination of infection that compromises the tooth function. Thorough knowledge about the root canal anatomy is one of the principal factors in achieving a successful outcome. The morphology of root canals is not always typical. Maxillary molars, known for varied morphology, require advanced imaging modalities such as cone-beam computed tomography (CBCT). This case report describes a series of four maxillary molars with different forms, numbers, and configurations of root canals and with unusual morphology, including a case of a third mesiobuccal (MB3) canal, a case of a second mesiobuccal (MB2) canal with two palatal canals [mesiopalatal (MP) and distopalatal (DP)], a case of three mesiobuccal canals (MB1, MB2, MB3), three distobuccal (DB1, DB2, DB3) canals, and two palatal canals [mesiopalatal (MP) and distopalatal (DP)], and a case of taurodontism, where different access cavity modifications, diagnostic methods, and magnifications were considered. https://fid.tums.ac.ir/index.php/fid/article/view/2058 https://fid.tums.ac.ir/index.php/fid/article/download/2058/1762