Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 7 2 2010 06 15 98 106 S. Marandi Dentist, Private Practice A. Bagherpour Assistant Professor, Department of Oral Radiology, School of Dentistry, Mashhad University of Medica M. Imanimoghaddam Associate Professor, Department of Oral Radiology, School of Dentistry, Mashhad University of Medica MR. Hatef Associate Professor, Department of Rheumatology, School of Medicine, Mashhad University of Medical S AR. Haghighi General Practitioner, Private Practice 2015 10 03 Objective: The aim of this cross-sectional analytic study was to evaluate the diagnostic efficacy of panoramic-based indices of the mandible (Mental Index-MI, Mandibular Cortical Index-MCI and Panoramic Mandibular Index-PMI) and to determine their correlation with bone mineral density (BMD) of the femoral neck and lumbar vertebrae (L2-L4) in order to assess the possibility of using these parameters as indicators of osteoporosis. Materials and Methods: The mandibular indices of 67 women over 35 years old were measured from panoramic radiographs, and bone densitometry was performed in the femoral neck and lumbar vertebrae (L2-L4), using DXA (Dual Energy X-ray Absorptiometry) technique. The patients were divided into three categories of normal, osteopenic and osteoporotic in each skeletal region. One-way ANOVA and ROC curve analyses were applied. The results were considered statistically significant when the P-value was less than 0.05. Results: Comparing the mean BMD in the femoral neck in women between C1 and C3 subgroups of MCI, a significant difference was detected (P=0.04). The mean PMI in the three skeletal subgroups was not different according to the skeletal region (P>0.05). We found a significant difference in mean MI between normal and osteopenic subgroups in the femoral neck (P=0.042). Conclusion: Using radiomorphometric indices of the mandible (MCI-MI) may be useful in determining the skeletal status of the patients, but is not sufficient for precise evaluation. https://fid.tums.ac.ir/index.php/fid/article/view/216 https://fid.tums.ac.ir/index.php/fid/article/download/216/216