Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 14 6 2017 12 16 352 360 EN Mohammad Javad Kharazifard PhD Candidate of Epidemiology, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Kurosh Holakouie-Naieni Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Ali Mansournia Assistant Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2017 12 16 2017 12 16 Multilevel analysis which was primarily introduced to deal with hierarchical data was later applied extensively for research in other fields of science and not only for nested data, but also for repeated measurements or clustered trials. This method of statistical analysis was applied in dental studies in the 1991 for the first time but despite its value for data analysis in dental studies, its application for dental studies remains limited until now. This manuscript reviews the applications of this method in dental studies. https://fid.tums.ac.ir/index.php/fid/article/view/2292 https://fid.tums.ac.ir/index.php/fid/article/download/2292/982