Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 15 6 2018 11 28 375 381 EN Amir Ghasemi Professor, Department of Restorative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran Alireza Sadr Associate Professor, Department of Restorative Dentistry, School of Dentistry, University of Washington, Washington, USA Anahita Pourhashemi Assistant Professor, Department of Restorative Dentistry, School of Dentistry, Hormozgan University of Medical Sciences, Hormozgan, Iran 2018 04 23 2018 08 23 Objective: This study assessed the effect of shelf life of a ceramic primer containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) monomer on microshear bond strength of zirconia ceramic to composite resin. Materials and Methods: Sixty-four sintered zirconia samples (1.5×5×7 mm) were pretreated with Clearfil Ceramic Primer (CCP) at baseline and after one, two and six months of storage at 6°C. Composite cylinders were fabricated using Tygon tubes (1 mm height, 0.7 mm diameter) and placed on treated zirconia blocks, light-cured and subjected to microshear bond strength test. Mode of failure was determined under a stereomicroscope. Fourier-transform infrared spectroscopy (FTIR) was performed at each storage time point. Data were analyzed using one-way ANOVA and Tukey’s test.  Results:  Significant differences were noted in microshear bond strength after six months of storage compared to baseline (P<0.05). Significant differences were noted in FTIR spectra at the four time points (P<0.05). Conclusions: The effectiveness of one-component ceramic primer in bonding to zirconia was significantly affected by the storage of this material in a time-dependent manner. Visible new peaks and changes in FTIR spectra over time indicated alterations in the composition of ceramic primer affecting its shelf life.   https://fid.tums.ac.ir/index.php/fid/article/view/2526