Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 12 1 2015 02 15 78 84 Ramin Foroughi Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran. Pouyan Amini Shakib Assistant Professor, Dental Research Center Dentistry Research Institute, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Alireza Babaei Darzi Post Graduate Student, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran. Maryam Seyedmajidi Associate Professor, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran. Naghmeh Jamaatlou Post Graduate Student, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran. 2015 10 16 Calcifying epithelial odontogenic tumor (CEOT) is an uncommon odontogenic tumor with well-known histopathological features and a challenging treatment plan. Although some investigators advocate conservative approach as the treatment of choice, others believe in radical surgical excision to avoid recurrence or malignant transformation. The main objective of this case report is presenting an unusual destructive recurrence of CEOT after 8 years in a 34-year-old woman, and discussing an effective treatment plan for this tumor. https://fid.tums.ac.ir/index.php/fid/article/view/361 https://fid.tums.ac.ir/index.php/fid/article/download/361/337