Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 11 5 2014 10 15 613 9 Andre Peisker Department of Cranio-Maxillofacial & Plastic Surgery, Jena University Hospital, Jena, Germany. Gregor Franziskus Raschke Department of Cranio-Maxillofacial & Plastic Surgery, Jena University Hospital, Jena, Germany. Arndt Guentsch Center of Dental Medicine, Jena University Hospital, Jena, Germany ; Department of Surgical Sciences, Marquette University, School of Dentistry, Milwaukee, Wisconsin, USA. Korosh Roshanghias Dentist, Private Practice, Berlin, Germany. Stefan Schultze-Mosgau Professor, Department of Cranio-Maxillofacial & Plastic Surgery, JenaUniversity Hospital, Jena, Germany. 2015 10 16 Oral surgery in patients with bleeding disorders is associated with a high risk of bleeding during and after surgery. This article is aimed to present the case of an eight-year-old girl suffering from severe Fanconi anemia with pancytopenia who underwent a dental extraction. The hemostatic effect of local administration of tranexamic acid in combination with a primary suture seems to be extremely helpful in order to reduce the necessity of blood products and the risk of postoperative bleeding. https://fid.tums.ac.ir/index.php/fid/article/view/372 https://fid.tums.ac.ir/index.php/fid/article/download/372/348