Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 20 0 2023 10 01 1 5 Pegah Sarraf Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran Sholeh Ghabraei Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Zahra Mohammadi Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Faranak Noori Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Nazanin Chitsaz Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran 2021 10 09 2022 09 09 This in-vitro study aimed to evaluate the physical properties of three resin-based root canal sealers (BETA RCS, AH26, and Adseal) in terms of flow and film thickness as per ISO 6876/2012. The results revealed that the flow values of BETA RCS, Adseal, and AH26 sealers were 23.06±1.58, 22.5±4.23, and 21.85±1.71, respectively. Moreover, film thickness values for BETA RCS, Adseal, and AH26 sealers were 52.33±2.51, 18.66±0.57, and 52±2, respectively. No significant difference was observed regarding film thickness between AH26 and BETA RCS sealers (P>0.05), while Adseal showed better result in terms of film thickness than other sealers (P˂0.05). The highest solubility was related to BETA RCS (0.6%), and the lowest to Adseal (0.07%). However, all sealers had acceptable solubility and radiopacity. The findings of the current study suggested that all tested root canal sealers had similar properties based on ISO 6876 standard criteria. https://fid.tums.ac.ir/index.php/fid/article/view/4228