Tehran University of Medical Sciences Frontiers in Dentistry 2676-296X 10 2 2013 03 15 141 6 Armita Rouhani Assistant Professor of Endodontics, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran. Jamileh Ghoddusi Neda Naghavi Zahra Ebadzadeh Majid Akbari 2015 10 16 The aim of this study was to compare the apical seal of curved canals obturated with Resilon/Epiphany with gutta-percha/AH Plus.Thirty-four extracted human mandibular molars with 25-40 degree canal curvature of the mesial root were selected for this study. After preparation, the mesiobuccal canals were obturated with gutta-percha and AH- Plus sealer (group G) or Resilon and Epiphany sealer (group R). Four specimens served as control. Microleakage was evaluated after passing 3 and 30 days using the fluid filtration technique. The data were analyzed statistically using parametric tests.In the 3-day evaluation, the mean microleakage in group R was significantly less than in group G (P< 0.05). After 30 days, there was no significant difference between the two groups (P> 0.05). In group G, the leakage values at the end of 30 days were significantly less than values at the end of 3 days. Although in group R the mean leakage decreased after 30 days, this reduction was not statistically significant.Resilon/Epiphany provided a better seal than gutta-percha/AH-Plus in severely curved root canals immediately after obturation, although with the passage of time, Resilon/Epiphany was equivalent to gutta-percha/AH Plus in sealing properties. https://fid.tums.ac.ir/index.php/fid/article/view/684 https://fid.tums.ac.ir/index.php/fid/article/download/684/659