Anti-Plaque and Anti-Gingivitis Efficacy of 0.25% Lemongrass Oil and 0.2% Chlorhexidine Mouthwash in Children
Abstract
Objectives: Research is ongoing to find safe and effective oral hygiene aids for oral self‑care in children. Mouthwashes are used to complete the process of mechanical plaque control. Lack of affordability and side effects of most commercially available mouthwashes limit their use in children. Hence, the cost-effective and easily available essential oil, lemongrass oil, when formulated as a mouthwash, may possibly serve as an adjunct to oral hygiene maintenance. The main objective of this study was to compare the efficacy of lemongrass oil and chlorhexidine (CHX) mouthwash in children.
Materials and Methods: Sixty healthy children between 9-12 years were selected. During the initial visit, the plaque pH, plaque index (PI), and gingival index (GI) were assessed, and oral prophylaxis was performed. The patients were randomized into three groups (n=20) and received 0.25% lemongrass oil mouthwash (group A), 0.2% CHX mouthwash (group B), and oral prophylaxis alone (group C). The patients were recalled after 14 and 21 days. ANOVA with post-hoc Bonferroni and paired t-test were used to analyze the results by SPSS software.
Results: Intragroup comparison of PI and GI showed a significant decrease between 14 and 21 days in groups A and B (P≤0.05). Intragroup comparison of the mean plaque pH in group A showed a significant increase at day 21 compared with baseline (P=0.028).
Conclusion: The results showed that the lemongrass oil mouthwash was effective in reducing PI and GI in children. Thus, it may be used as a good herbal alternative to CHX mouthwash.
2. Jenabian N, Akbar AM, Karami E, Bejeh PM. The effect of Camellia Sinensis (green tea) mouthwash on plaque-induced gingivitis: a single-blinded randomized controlled clinical trial. 2012 Dec;20(1):1-6.
3. Shaddox ML, Karina SM. Periodontal Disease in Children and Adolescents: A masked Reality. Pediatr Dent Care. 2016;2:1-2.
4. Christopher V Hughes, Jeffrey A Dean. Mechanical and chemotherapeutic home oral hygiene. In: David R. Avery, Ralph E. McDonald, Jeffrey A. Dean. Dentistry for the Child and Adolescent. (8th edition. Mosby. Missouri;2004:416.
5. Hambire CU, Jawade R, Patil A, Vaibhav R, Ankur A, Nehete PB. Comparing the antiplaque efficacy of 0.5% Camellia sinensis extract, 0.05% sodium fluoride, and 0.2% chlorhexidine gluconate mouthwash in children. J Int Soc Prevent Communit Dent. 2015 May;5(3):218-26.
6. Chhina S, Avnish S, Ipseeta M, Rickypal S, Anubhav S, Aggarwal V. A randomized clinical study for comparative evaluation of Aloe Vera and 0.2% chlorhexidine gluconate mouthwash efficacy on de-novo plaque formation. J Int Soc Prev Community Dent. 2016 May;6(3):251-5.
7. Chouhan S, Sharma K, Guleria S. Antimicrobial activity of some essential oils: present status and future perspectives. Medicines.2017 Sep;4(3):58.
8. Mohamed NB, Mohamed AF, Abdel K, Fairouz S, Hadjer TK. Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan J Med. 2014 Jan;9(1):25431.
9. Han X, Parker TL. Lemongrass (Cymbopogon flexuosus) essential oil demonstrated anti-inflammatory effect in pre-inflamed human dermal fibroblasts. Biochimie Open .2017 Jun;4:107-11.
10. Nayak AK, Panigrahi PP. Solubility enhancement of etoricoxib by cosolvency approach.ISRN.2012;2012:1-5.
11. Fosdick LS, Englander HR, Hoerman KC, Kesel RG. A comparison of pH values of in vivo dental plaque after sucrose and sorbital mouth rinses. J Am Dent Assoc 1957 Aug;55(2):191-5.
12. Silness J, Loe H. Periodontal disease in pregnancy: II correlation between oral hygiene and periodontal condition. Acta Odontol Scand. 1964 Feb;22:121-35.
13. Loe H, Silness J. Periodontal disease in pregnancy: I. prevalence and severity. Acta Odontol Scand. 1963 Dec;21:533-51.
14. Axelsson, J. Lindhe. Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. Results after 6 years. J Clin Periodontol.1981 Jun;8(3):239-48.
15. Axelsson, J. Lindhe, B. Nystrom on the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. J Clin Periodontol.1991 Mar;18(3):182-9.
16. Kolliyavar B, Shettar L, Thakur S. Chlorhexidine: the gold standard mouth wash. J Pharm Biomed Sci 2016 Feb;6(2):106-9.
17. Naik IM, Fomda BA, Jaykumar E, Bhat JA. Antibacterial activity of lemongrass (Cymbopogon citratus) oil against some selected pathogenic bacterias. Asian Pac J Trop Med. 2010 Aug;3(7):535-8.
18. Garg D, Karuna YM, Srikant N, Bandary M, Anupama P, Arathi R. Evaluation of plaque pH changes following consumption of health drinks by children: A pilot study. J Clin Diagn Res. 2017 May;11(5):ZC05-8.
19. Muralikrishnan K, Asokan S, Priya PR. Effect of different chewing gums on dental plaque pH, salivary pH, and buffering capacity in children: A randomized controlled trial. SRM J Res Dent Sci.2018 Oct;9(4):158-63.
20. Talreja N, Devendrappa SN, Singla SS,
Agrawal N, Mali S. An in vivo comparison of plaque pH changes in children aged 8-12 years after consumption of milk and green tea with sugar. J Int Oral Health. 2018 Jan;10(1):10-15.
21. Kukkamalla AM, Bhat GS, Pentapati KC, Goyal R. Antiplaque efficacy of lemongrass oil mouthwash – an in-vitro study. Glob J Med Res.2012;12(7):19-24.
22. Biswas G, Anup N, Acharya S, Kumawat H, Vishnani P, Tambi S. Evaluation of the efficacy of 0.2% chlorhexidine versus herbal oral rinse on plaque induced gingivitis- A randomized clinical trial. J Nurs Health Sci. 2014 Mar;3(2):58-63.
23. Dany S, Mohanty P, Tangade P, Rajput P, Batra M. Efficacy of 0.25% lemongrass oil mouthwash: A three arm prospective parallel clinical study. J Clin Diagn Res. 2015 Oct,9(10):ZC13-7.
24. Dany SS, Pradeep T. Periodontal therapy with 0.25%lemongrass oil mouthwash in reducing risk of cardiovascular diseases: a 3-arm prospective parallel experimental study. Ethiop J Health Sci. 2017 Sep; 27(5):531-40.
Issue | Vol 18 (Continuously Published Article-Based) | |
Section | Original Article | |
DOI | https://doi.org/10.18502/fid.v18i32.7237 | |
Keywords | ||
Gingivitis Chlorhexidine; Mouthwashe Lemongrass Oil; Dental Plaque |
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