The Effect of Dimethyl Sulfoxide on the Microtensile Bond Strength of Universal Adhesives to Dentin
-
Zahra Dadvar
,
Mohammad Esmaeel Ebrahimi Chaharom
,
Soodabeh Kimyai
,
Mahmoud Bahari
,
Mehdi Daneshpooy
Abstract
Objectives: The goal of this investigation was to see how a dentin pretreatment with 5% DMSO affected the microtensile bond strength (μTBS) of universal adhesives.
Materials and Methods: In terms of adhesive kind and etching procedure, 32 healthy third human molars were randomly separated into eight groups. Three universal adhesives with etch-and-rinse and self-etch strategies (G-Premio Bond: GPB.ER/SE, All-Bond Universal: ABU.ER/SE, Prime & Bond Elect: PBE.ER/SE), one two-stage self-etch adhesive (Clearfil SE Bond: CSB), and one two-stage etch-and-rinse adhesive (Adper Single Bond 2: ASB) were employed in with and without DMSO modes (group/N=16). Dentin pretreatment was conducted with 50 μl of 5% DMSO, followed by the use of an adhesive. The μTBS of samples was tested. The influence of adhesive type and DMSO application on bond strength was evaluated using a two-way analysis of variance (ANOVA) (=0.05).
Results: The dentin-adhesive μTBS was significantly affected by DMSO administration (P=0.003), type of adhesive (P=0.001), and the combination of DMSO application and type of adhesive (P=0.027). In the DMSO application mode, the average bond strength of universal adhesives with etch and rinse mode was significantly higher than in the non-application mode, but in the self-etch technique, there was no significant difference pattern between DMSO applications and non-application modes in terms of adhesive bond strength.
Conclusion: The use of DMSO in an etch-and-rinse technique can dramatically enhance the universal adhesive-dentin μTBS and has promise benefits for clinicians in terms of enhancing dentin bond performance.
1. Guo J, Lei W, Yang H, Zhang Y, Zhao S, Huang C. Dimethyl Sulfoxide Wet-bonding Technique May Improve the Quality of Dentin Bonding. J Adhes Dent. 2017 Jun 8:229-237.
2. Stape TH, Tjäderhane L, Tezvergil-Mutluay A, Yanikian CR, Szesz AL, Loguercio AD, Martins LR. Dentin bond optimization using the dimethyl sulfoxide-wet bonding strategy: A 2-year in vitro study. Dent Mater. 2016 Dec;32(12):1472-1481.
3. Salim Al-Ani AAS, Scarabello Stape TH, Mutluay M, Tjäderhane L, Tezvergil-Mutluay A. Incorporation of dimethyl sulfoxide to model adhesive resins with different hydrophilicities: Physico/mechanical properties. J Mech Behav Biomed Mater. 2019 May;93:143-150.
4. Tjäderhane L, Mehtälä P, Scaffa P, Vidal C, Pääkkönen V, Breschi L, Hebling J, Tay FR, Nascimento FD, Pashley DH, Carrilho MR. The effect of dimethyl sulfoxide (DMSO) on dentin bonding and nanoleakage of etch-and-rinse adhesives. Dent Mater. 2013 Oct;29(10):1055-62.
5. Chaharom ME, Bahari M, Rahbar M, Golbaz S. Effect of galardin and its solvents on the microtensile bond strength of different adhesive systems to dentin. Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 2019 Sep 2;19:e4438.
6. Stape THS, Tjäderhane L, Abuna G, Sinhoreti MAC, Martins LRM, Tezvergil-Mutluay A. Optimization of the etch-and-rinse technique: New perspectives to improve resin-dentin bonding and hybrid layer integrity by reducing residual water using dimethyl sulfoxide pretreatments. Dent Mater. 2018 Jul;34(7):967-977.
7. Nagarkar S, Theis-Mahon N, Perdigão J. Universal dental adhesives: Current status, laboratory testing, and clinical performance. J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):2121-2131.
8. van Dijken JW, Pallesen U. Three-year Randomized Clinical Study of a One-step Universal Adhesive and a Two-step Self-etch Adhesive in Class II Composite Restorations. J Adhes Dent. 2017;19(4):287-294.
9. Oz FD, Kutuk ZB, Ozturk C, Soleimani R, Gurgan S. An 18-month clinical evaluation of three different universal adhesives used with a universal flowable composite resin in the restoration of non-carious cervical lesions. Clin Oral Investig. 2019 Mar;23(3):1443-1452.
10. Arbildo-Vega H, Lamas-Lara C, Cruzado-Oliva F, Rosas-Prado C, Gómez-Fuertes A, Vásquez-Rodrigo H. Comparison of the clinical effect of the adhesive strategies of universal adhesives in the treatment of non-carious cervical lesions. Systematic review and meta-analysis. J Oral Res. 2018 May 31;7(5):210-22.
11. Sharafeddin F, Nouri H, Koohpeima F. The Effect of Temperature on Shear Bond Strength of Clearfil SE Bond and Adper Single Bond Adhesive Systems to Dentin. J Dent (Shiraz). 2015 Mar;16(1):10-6.
12. Sharafeddin F, Salehi R, Feizi N. Effect of Dimethyl Sulfoxide on Bond Strength of a Self-Etch Primer and an Etch and Rinse Adhesive to Surface and Deep Dentin. J Dent (Shiraz). 2016 Sep;17(3 Suppl):242-249.
13. Stape TH, Tjäderhane L, Marques MR, Aguiar FH, Martins LR. Effect of dimethyl sulfoxide wet-bonding technique on hybrid layer quality and dentin bond strength. Dent Mater. 2015 Jun;31(6):676-83.
14. Shafiei F, Memarpour M, Sarafraz Z. Effect of dimethyl sulfoxide on bond durability of fiber posts cemented with etch-and-rinse adhesives. J Adv Prosthodont. 2016 Aug;8(4):251-8.
15. Stape TH, Tezvergil-Mutluay A, Mutluay MM, Martins LR, do Prado RL, Pizi EC, Tjäderhane L. Influence of dimethyl sulfoxide used as a solvent on the physical properties and long-term dentin bonding of hydrophilic resins. J Mech Behav Biomed Mater. 2016 Dec;64:220-8.
16. Nagpal R, Mehmood N, Singh U. Enhancing the resin-dentin bond with DMSO: A narrative review. Glob J Oral Sci. 2019;5:40-6.
17. Isolan CP, Valente LL, Münchow EA, Basso GR, Pimentel AH, Schwantz JK, et al. Bond strength of a universal bonding agent and other contemporary dental adhesives applied on enamel, dentin, composite, and porcelain. Applied Adhesion Science. 2014 Dec;2:1-0.
18. Mehtälä P, Pashley DH, Tjäderhane L. Effect of dimethyl sulfoxide on dentin collagen. Dent Mater. 2017 Aug;33(8):915-922.
19. Rosa WL, Piva E, Silva AF. Bond strength of universal adhesives: A systematic review and meta-analysis. J Dent. 2015 Jul;43(7):765-76.
20. Muñoz MA, Sezinando A, Luque-Martinez I, Szesz AL, Reis A, Loguercio AD, Bombarda NH, Perdigão J. Influence of a hydrophobic resin coating on the bonding efficacy of three universal adhesives. J Dent. 2014 May;42(5):595-602.
21. Wagner A, Wendler M, Petschelt A, Belli R, Lohbauer U. Bonding performance of universal adhesives in different etching modes. J Dent. 2014 Jul;42(7):800-7.
22. Muñoz MA, Luque I, Hass V, Reis A, Loguercio AD, Bombarda NH. Immediate bonding properties of universal adhesives to dentine. J Dent. 2013 May;41(5):404-11.
23. Luque-Martinez IV, Perdigão J, Muñoz MA, Sezinando A, Reis A, Loguercio AD. Effects of solvent evaporation time on immediate adhesive properties of universal adhesives to dentin. Dent Mater. 2014 Oct;30(10):1126-35.
24. Szesz AL, Pereira GMA, Siqueira FSF, Cardenas AFM, Bandeca MC, Armas-Vega A, Reis A, Loguercio AD. Effect of Addition of Dimethyl Sulfoxide to Simplified Adhesives on Dentin Bond Durability after Three Years of Water Storage. J Adhes Dent. 2021 Apr 7;23(2):159-165.
25. Stape THS, Uctasli M, Cibelik HS, Tjäderhane L, Tezvergil-Mutluay A. Dry bonding to dentin: Broadening the moisture spectrum and increasing wettability of etch-and-rinse adhesives. Dent Mater. 2021 Nov;37(11):1676-1687.
26. Sangavi Sithu Balakrishnan DS, Naik R. Influence of novel dry bonding approaches on the shear bond strength of a universal adhesive: An in vitro study. Int J Appl Dent Sci. 2021; 7(1): 241-4
27. Zhang Z, Yu J, Yao C, Yang H, Huang C. New perspective to improve dentin-adhesive interface stability by using dimethyl sulfoxide wet-bonding and epigallocatechin-3-gallate. Dent Mater. 2020 Nov;36(11):1452-1463.
28. Venkataramanan NS. Microsolvation of DMSO: Density functional study on the structure and polaraizabilities. Int J Quantum Chem. 2012 Jul 5;112(13):2599-606.
29. Mehtälä P, Agee K, Breschi L, Pashley DH, Tjäderhane L. Proprietary solvent enhances dentin wettability. Dent Mater. 2010(26):e12-3.
30. Tjäderhane L, Nascimento FD, Breschi L, Mazzoni A, Tersariol IL, Geraldeli S, Tezvergil-Mutluay A, Carrilho MR, Carvalho RM, Tay FR, Pashley DH. Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins. Dent Mater. 2013 Jan;29(1):116-35.
31. Hiraishi N, Tochio N, Kigawa T, Otsuki M, Tagami J. Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR. J Dent. 2014 Apr;42(4):484-9.
32. Hebling J, Bianchi L, Basso FG, Scheffel DL, Soares DG, Carrilho MR, Pashley DH, Tjäderhane L, de Souza Costa CA. Cytotoxicity of dimethyl sulfoxide (DMSO) in direct contact with odontoblast-like cells. Dent Mater. 2015 Apr;31(4):399-405.
33. Geurtsen W, Lehmann F, Spahl W, Leyhausen G. Cytotoxicity of 35 dental resin composite monomers/additives in permanent 3T3 and three human primary fibroblast cultures. J Biomed Mater Res. 1998 Sep 5;41(3):474-80.
2. Stape TH, Tjäderhane L, Tezvergil-Mutluay A, Yanikian CR, Szesz AL, Loguercio AD, Martins LR. Dentin bond optimization using the dimethyl sulfoxide-wet bonding strategy: A 2-year in vitro study. Dent Mater. 2016 Dec;32(12):1472-1481.
3. Salim Al-Ani AAS, Scarabello Stape TH, Mutluay M, Tjäderhane L, Tezvergil-Mutluay A. Incorporation of dimethyl sulfoxide to model adhesive resins with different hydrophilicities: Physico/mechanical properties. J Mech Behav Biomed Mater. 2019 May;93:143-150.
4. Tjäderhane L, Mehtälä P, Scaffa P, Vidal C, Pääkkönen V, Breschi L, Hebling J, Tay FR, Nascimento FD, Pashley DH, Carrilho MR. The effect of dimethyl sulfoxide (DMSO) on dentin bonding and nanoleakage of etch-and-rinse adhesives. Dent Mater. 2013 Oct;29(10):1055-62.
5. Chaharom ME, Bahari M, Rahbar M, Golbaz S. Effect of galardin and its solvents on the microtensile bond strength of different adhesive systems to dentin. Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 2019 Sep 2;19:e4438.
6. Stape THS, Tjäderhane L, Abuna G, Sinhoreti MAC, Martins LRM, Tezvergil-Mutluay A. Optimization of the etch-and-rinse technique: New perspectives to improve resin-dentin bonding and hybrid layer integrity by reducing residual water using dimethyl sulfoxide pretreatments. Dent Mater. 2018 Jul;34(7):967-977.
7. Nagarkar S, Theis-Mahon N, Perdigão J. Universal dental adhesives: Current status, laboratory testing, and clinical performance. J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):2121-2131.
8. van Dijken JW, Pallesen U. Three-year Randomized Clinical Study of a One-step Universal Adhesive and a Two-step Self-etch Adhesive in Class II Composite Restorations. J Adhes Dent. 2017;19(4):287-294.
9. Oz FD, Kutuk ZB, Ozturk C, Soleimani R, Gurgan S. An 18-month clinical evaluation of three different universal adhesives used with a universal flowable composite resin in the restoration of non-carious cervical lesions. Clin Oral Investig. 2019 Mar;23(3):1443-1452.
10. Arbildo-Vega H, Lamas-Lara C, Cruzado-Oliva F, Rosas-Prado C, Gómez-Fuertes A, Vásquez-Rodrigo H. Comparison of the clinical effect of the adhesive strategies of universal adhesives in the treatment of non-carious cervical lesions. Systematic review and meta-analysis. J Oral Res. 2018 May 31;7(5):210-22.
11. Sharafeddin F, Nouri H, Koohpeima F. The Effect of Temperature on Shear Bond Strength of Clearfil SE Bond and Adper Single Bond Adhesive Systems to Dentin. J Dent (Shiraz). 2015 Mar;16(1):10-6.
12. Sharafeddin F, Salehi R, Feizi N. Effect of Dimethyl Sulfoxide on Bond Strength of a Self-Etch Primer and an Etch and Rinse Adhesive to Surface and Deep Dentin. J Dent (Shiraz). 2016 Sep;17(3 Suppl):242-249.
13. Stape TH, Tjäderhane L, Marques MR, Aguiar FH, Martins LR. Effect of dimethyl sulfoxide wet-bonding technique on hybrid layer quality and dentin bond strength. Dent Mater. 2015 Jun;31(6):676-83.
14. Shafiei F, Memarpour M, Sarafraz Z. Effect of dimethyl sulfoxide on bond durability of fiber posts cemented with etch-and-rinse adhesives. J Adv Prosthodont. 2016 Aug;8(4):251-8.
15. Stape TH, Tezvergil-Mutluay A, Mutluay MM, Martins LR, do Prado RL, Pizi EC, Tjäderhane L. Influence of dimethyl sulfoxide used as a solvent on the physical properties and long-term dentin bonding of hydrophilic resins. J Mech Behav Biomed Mater. 2016 Dec;64:220-8.
16. Nagpal R, Mehmood N, Singh U. Enhancing the resin-dentin bond with DMSO: A narrative review. Glob J Oral Sci. 2019;5:40-6.
17. Isolan CP, Valente LL, Münchow EA, Basso GR, Pimentel AH, Schwantz JK, et al. Bond strength of a universal bonding agent and other contemporary dental adhesives applied on enamel, dentin, composite, and porcelain. Applied Adhesion Science. 2014 Dec;2:1-0.
18. Mehtälä P, Pashley DH, Tjäderhane L. Effect of dimethyl sulfoxide on dentin collagen. Dent Mater. 2017 Aug;33(8):915-922.
19. Rosa WL, Piva E, Silva AF. Bond strength of universal adhesives: A systematic review and meta-analysis. J Dent. 2015 Jul;43(7):765-76.
20. Muñoz MA, Sezinando A, Luque-Martinez I, Szesz AL, Reis A, Loguercio AD, Bombarda NH, Perdigão J. Influence of a hydrophobic resin coating on the bonding efficacy of three universal adhesives. J Dent. 2014 May;42(5):595-602.
21. Wagner A, Wendler M, Petschelt A, Belli R, Lohbauer U. Bonding performance of universal adhesives in different etching modes. J Dent. 2014 Jul;42(7):800-7.
22. Muñoz MA, Luque I, Hass V, Reis A, Loguercio AD, Bombarda NH. Immediate bonding properties of universal adhesives to dentine. J Dent. 2013 May;41(5):404-11.
23. Luque-Martinez IV, Perdigão J, Muñoz MA, Sezinando A, Reis A, Loguercio AD. Effects of solvent evaporation time on immediate adhesive properties of universal adhesives to dentin. Dent Mater. 2014 Oct;30(10):1126-35.
24. Szesz AL, Pereira GMA, Siqueira FSF, Cardenas AFM, Bandeca MC, Armas-Vega A, Reis A, Loguercio AD. Effect of Addition of Dimethyl Sulfoxide to Simplified Adhesives on Dentin Bond Durability after Three Years of Water Storage. J Adhes Dent. 2021 Apr 7;23(2):159-165.
25. Stape THS, Uctasli M, Cibelik HS, Tjäderhane L, Tezvergil-Mutluay A. Dry bonding to dentin: Broadening the moisture spectrum and increasing wettability of etch-and-rinse adhesives. Dent Mater. 2021 Nov;37(11):1676-1687.
26. Sangavi Sithu Balakrishnan DS, Naik R. Influence of novel dry bonding approaches on the shear bond strength of a universal adhesive: An in vitro study. Int J Appl Dent Sci. 2021; 7(1): 241-4
27. Zhang Z, Yu J, Yao C, Yang H, Huang C. New perspective to improve dentin-adhesive interface stability by using dimethyl sulfoxide wet-bonding and epigallocatechin-3-gallate. Dent Mater. 2020 Nov;36(11):1452-1463.
28. Venkataramanan NS. Microsolvation of DMSO: Density functional study on the structure and polaraizabilities. Int J Quantum Chem. 2012 Jul 5;112(13):2599-606.
29. Mehtälä P, Agee K, Breschi L, Pashley DH, Tjäderhane L. Proprietary solvent enhances dentin wettability. Dent Mater. 2010(26):e12-3.
30. Tjäderhane L, Nascimento FD, Breschi L, Mazzoni A, Tersariol IL, Geraldeli S, Tezvergil-Mutluay A, Carrilho MR, Carvalho RM, Tay FR, Pashley DH. Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins. Dent Mater. 2013 Jan;29(1):116-35.
31. Hiraishi N, Tochio N, Kigawa T, Otsuki M, Tagami J. Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR. J Dent. 2014 Apr;42(4):484-9.
32. Hebling J, Bianchi L, Basso FG, Scheffel DL, Soares DG, Carrilho MR, Pashley DH, Tjäderhane L, de Souza Costa CA. Cytotoxicity of dimethyl sulfoxide (DMSO) in direct contact with odontoblast-like cells. Dent Mater. 2015 Apr;31(4):399-405.
33. Geurtsen W, Lehmann F, Spahl W, Leyhausen G. Cytotoxicity of 35 dental resin composite monomers/additives in permanent 3T3 and three human primary fibroblast cultures. J Biomed Mater Res. 1998 Sep 5;41(3):474-80.
| Issue | Vol 21 (Continuously Published Article-Based) | |
| Section | Original Article | |
| DOI | https://doi.org/10.18502/fid.v21i36.16474 | |
| Keywords | ||
| Dentin-Bonding Agents Adhesives Dimethyl Sulfoxide Dental Bonding | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Dadvar Z, Ebrahimi Chaharom ME, Kimyai S, Bahari M, Daneshpooy M. The Effect of Dimethyl Sulfoxide on the Microtensile Bond Strength of Universal Adhesives to Dentin. Front Dent. 2024;21.
